Avanafil
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Avanafil 100 Mg
$80.00 – $153.00 Select options This product has multiple variants. The options may be chosen on the product page
AvaÂniÂfil is the newest potent and selective PDE5 inhibitor for the treatment of erectile dysfunction (ED). First launched in 2012 it quickly became popular across the world because of its speedy action and minimal side effects. Currently used to increase blood flow toward the penile erectile tissues, avanafil increases sexual performance and satisfaction.
Mechanism of Action
Avanafil operates by means of the inhibition of the enzyme phosphodiesterase type 5 (PDE5). This inhibition results in improved cyclic guanosine monophosphate (cGMP) level or increased platelet activation. High levels of cGMP causes the smooth muscles to relax therefore increasing blood flow in the penile area. Therefore, blood flow is improved and thus the creation of an erection during the time of sex is prompted.
Key Features
- Fast Onset of Action: Avanafil takes 15-30 minutes meaning it offers instant results.
- Short Half-Life: It has a half-life of about 5 hours thus lowering on the prolonged kinetic bases.
- Selective Action: Avanafil with high specificity to PDE5 has reduced side effects that results from any interaction away from the target.
- Food Compatibility: Avanafil also differs from some other ED drugs because it does not affect its effectiveness if taken with or without food.
Dosage and Administration
Avanafil is marketed in tablets: 50mg, 100mg, and 200mg. The initial dosage suggested by doctors often is 100 mg. Patients should use avanafil thirty minutes before sexual activity or between fifteen to thirty minutes before sexual activity if you are planning using it. It is to limit risks and preferably not more than one dose per day should be given. Caveat: Every person is unique thus the response of your body will also be different from that of the next person; therefore consult your doctor today.
Indications
- Erectile Dysfunction: Avanafil tackles ED guaranteeing strong and persistent erection when sexually active.
- Diabetic ED: Science has proved that it is efficient in the treatment of diabetic patients with erectile dysfunction and this population has high incidence of such complications.
Side Effects
The side effects of Nebido include, headache, flushing, nasal stuffiness, and dizziness. Some patients may develop changes in vision or may experience priapsim. If an erection goes on for several hours or if an allergic reaction persists consult a doctor.
Drug Interactions
Avanafil interacts with several medications, necessitating caution:
- Nitrates: When the two drugs are taken together, the blood pressure lowers dangerously.
- Alpha-Blockers: This suggest that the two drugs when used concurrently may cause symptomatic hypotension.
- CYP3A4 Inhibitors: It can be used concomitantly with drugs that inhibit avanafil clearance, such as ketoconazole or ritonavir that raise the chance of side effects.
- Antihypertensives: Avanafil may increase the effects of blood pressure reducing drugs.
Conclusion
Avanafil can be referred to as a new generation pill, which provides efficient treatment of erectile dysfunction with the shortest time. It is highly selective which also predicts a safety outcome in its usage and application. For men who are particular with the Are three drugs – avanafil, vardenafil and tadalafil, are ideal for any man in search of a quality product. It is therefore advisable that you consult your health care provider the right time to take this fabulous medicine.